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New drug target emerges for a dangerous fungal pathogen

Cryptococcus neoformans is a fungal pathogen usually affecting immunocompromised patients, particularly AIDS and organ transplant patients, and is one that can be lethal. Current treatments against cryptococcosis are often not effective. Now a team of researchers led by Stony Brook University scientists Mansa Munshi and Maurizio Del Poeta in the Department of Molecular Genetics & Microbiology, have discovered a novel gene that helps understand the mechanism of survival of this pathogen in various host conditions.

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