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Novel therapy holds promise of remission in relapsed patients with diffuse...

A phase 2 clinical trial of a novel therapy for patients who have experienced a relapse of diffuse large B-cell lymphoma (DLBCL) resulted in extended remission, averaging 14.5 months, and longer than...

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Novel schistosomiasis vaccine: New phase of clinical studies

The Oswaldo Cruz Foundation (Fiocruz) at Rio de Janeiro, Brazil, will start the phase II clinical trials of a vaccine for schistosomiasis, called 'Sm14 Vaccine'. The initiative is one of the health...

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Fewer cardiovascular drugs being studied in clinical trials

The number of cardiovascular drugs in the research pipeline has declined across all phases of development in the last 20 years even as cardiovascular disease has become the number one cause of death...

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Drug targeting tumor metabolism enters clinical trial

The University of Texas MD Anderson Cancer Center's Institute for Applied Cancer Science (IACS) has initiated the first clinical study of a novel drug designed to starve cancer cells, IACS-10759. The...

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DNA-based Zika vaccine showed protection from infection, brain damage and death

As the global spread of the Zika virus continues, efforts are underway to halt the disease's transmission. While no licensed therapies or vaccines to protect against the Zika virus are currently...

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New drug for heart disease shows promise for cats and humans

A new drug shows promise for treating heart disease in cats and humans, according to research by a team including veterinarians at the University of California, Davis, School of Veterinary Medicine.

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Marijuana compounds show promise in treatment of cardiac disease

A Nevada company is hoping to develop new medicines for heart failure using compounds in marijuana and a novel therapy identified by a University of Hawaiʻi at Mānoa researcher.

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Researchers discover cancer treatment for transplant patients

Kenar D. Jhaveri, MD, and Richard Barnett, MD, Feinstein Institute for Medical Research scientists and Northwell Health Department of Internal Medicine nephrologists, published a Letter to the Editor...

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Genetic defect found to cause disease in multiple organs

New research from Queen Mary University of London (QMUL) has identified a novel syndrome in patients with kidney and adrenal disease.

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Elimination of specific neurons outside the brain triggers obesity

A research team led by Ana Domingos, from Instituto Gulbenkian de Ciencia (IGC; Portugal) has developed a new genetic technique that eliminates specific neurons of the peripheral nervous system without...

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Gonorrhoea treatment reaching crisis point

The threat of increased antibiotic resistance is often in the headlines. Now two Massey University researchers argue that in the case of sexually-transmitted gonorrhoea, this is inevitable, and we had...

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African plant extract offers new hope for Alzheimer's

A plant extract used for centuries in traditional medicine in Nigeria could form the basis of a new drug to treat Alzheimer's disease, researchers at The University of Nottingham have found.

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Potential new treatments and tools for understanding depression

ANSTO Human Health researchers have co-led an international team investigating new treatments for depression. This research, recently published in the European Journal of Medicinal Chemistry, by a...

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No dye: Cancer patients' gray hair darkened on immune drugs

Cancer patients' gray hair unexpectedly turned youthfully dark while taking novel drugs, and it has doctors scratching their heads.

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Scientists identify a possible therapeutic target for regulating body weight

A new study published online in The FASEB Journal reveals a novel gene involved in maintaining body weight. Specifically, the study suggests that GTRAP3-18 interacts with pro-opiomelanocortin (POMC) in...

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Researchers find mechanism involved in novel drug design with potential to...

A team of researchers from Instituto de Medicina Molecular (iMM) Lisboa successfully used a new method to chemically modify a protein's components. Their results have potential medical applications and...

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Scientists observe tremors associated with Parkinson's disease in fruit flies

Scientists say they have a better understanding of the tremors commonly associated with Parkinson's disease after observing the movements in fruit flies.

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Domestic travel key to distribution of flu across Australia

New scientific research on the spread of flu across Australia has revealed that all major cities appear to experience outbreaks of flu around the same time each year, published today in PLOS Pathogens.

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A new ecosystem approach to fight antibiotic resistance

The World Health Organization (WHO) has deemed antibiotic resistance to be one of the three greatest threats to human health today, as bacteria become increasingly resistant and too few treatments are...

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Bacteria block transmission of Zika and Dengue viruses

Scientists at the University of Glasgow's MRC Centre for Virus Researchopens (CVR) have found a bacterial strain which blocks dengue and Zika virus transmission from mosquitoes.

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